A key concept of a VRE (Virtual Research Environment) is that organisations can deploy their own VRE for their own purposes, deploy whatever applications they need and integrate it with their own security infrastructure. Deployments to in-house hardware and cloud infrastructure (e.g Amazon EC2) are possible.

A VRE can be deployed to a single computer (even a  laptop) or a cluster of 10's or 100's of servers.

Detailed instructions for doing this are contained in the Wiki.